Preston vs Tottenham LIVE updates as Son scores twice, Danjuma ...

Here are Alasdair's thoughts on that Spurs line-up

It's a much-changed line-up from Antonio Conte and it's a team with enough experience on paper to do the job, but how many times have we said that before?

Richarlison misses out with a minor knock when he would likely have started which means Ivan Perisic pushes forward alongside Son Heung-min and Dejan Kulusevski. Harry Kane gets to spend at least the start of a match on the bench for the first time this season, doing so alongside new signing Arnaut Danjuma.

It's a rare chance to see Yves Bissouma and Rodrigo Bentancur as a pairing while Matt Doherty and Ryan Sessegnon will be expected to provide the thrust down the flanks.

Oliver Skipp edges ahead of Pape Matar Sarr for the central midfield bench spot again alongside Pierre-Emile Hojbjerg. Those linked with a loan move have varying degrees of involvement, Bryan Gil on the bench and Djed Spence not even in the squad.

It's a makeshift back three with Davinson Sanchez in the centre, a role he hasn't always looked comfortable in, and the Colombian captains the side.

World Cup finalists Hugo Lloris and Cristian Romero, who won the competition, both get the weekend off.

It's a 3-4-3 without Kane for the first time this season and it comes in the one competition Spurs have the best chance of progressing far in, as Premier League clubs tumble out of it each round. They cannot afford to put in a similar performance to the one that sent them spiralling out of it at Middlesbrough last season in front of a noisy crowd.